Language maps signals onto meanings through the use of two distinct types of structure. First, the space of meanings is discretized into categories that are shared by all users of the language. Second, the signals employed by the language are compositional: The meaning of the whole is a function of its parts and the way in which those parts are combined. In three iterated learning experiments using a vast, continuous, open-ended meaning space, we explore the conditions under which both structured (...) categories and structured signals emerge ex nihilo. While previous experiments have been limited to either categorical structure in meanings or compositional structure in signals, these experiments demonstrate that when the meaning space lacks clear preexisting boundaries, more subtle morphological structure that lacks straightforward compositionality—as found in natural languages—may evolve as a solution to joint pressures from learning and communication. (shrink)

Modern information technologies, beginning with the fax and audiocassettes but now exemplified in satellite television and the Internet, have opened the public discourse of Islam to new voices and, more subtlely, to new practices. While media-savvy militants draw the attention of outside observers, a quieter drama is unfolding. Pious middle classes are extending conventional patterns of seeking out religious guidance into new channels, particularly the Internet; the continuous search for role models and reference groups is meeting increasingly modern ways of (...) providing those - namely, media and increasingly media that target specific needs of growing middle classes. These range from religious instructional material for children to be used by parents to religious advice columnists, both conventional and contemporary to sermons to selections of news. Once 'private' discourses are on public display, and this public world of Islam is decidedly intimate. Where scholars of print note an officialization of discourse that moves into that medium, and programmatic 'islamizers' of knowledge, politics, etc. generally pursue entextualization strategies, electronic communication is moving Islam into the marketplace and aligning its practices, both metaphorically in the sense that the range of public choice and alternatives expands and literally in the rise of businesses to service these demands. (shrink)

I. SummaryRuth Boeker's Locke on Persons and Personal Identity is a profound treatment of Locke's views on the nature and identity of human persons. The book is divided roughly into two halves. The first half (Chapters 1–6 and 8) focuses on providing a philosophically sophisticated interpretation of Locke that engages with the most recent secondary literature. Chapter 3, for instance, includes an important contribution to scholarly debates about Locke's sortal-relative account of identity in the Essay II.xxvii.§7–8. Some (the coincidence theorists) (...) have argued that Locke's claim that there are different persistence conditions for a ‘man’ (human animal) and the ‘mass of matter’ that occupies the same spatio-temporal location as the man entails that there are two, coincident material objects. Others (the relative identity theorists) argue that Locke holds that there is ontologically one and only one material object at any spatio-temporal location—a single object that can be attributed different identity conditions when considered under different sortals. (shrink)

This paper outlines the views of two 17th century thinkers on the question of the metaphysics of resurrection. I show that Jackson and Locke each depart from central 17th century Scholastic convictions regarding resurrection and philosophical anthropology. Each holds that matter or material continuity is not a plausible principle of diachronic individuation for living bodies such as human beings. Despite their rejection of the traditional view, they each provide a defence of the possibility of a personal afterlife. I outline these (...) defences in sections III–IV. I then argue that it is likely either that Locke had read Jackson on the issue of resurrection or that the two were influenced by a common source. I argue that matter might provide a suitable principle of diachronic individuation in both everyday cases of living bodies and in the case of resurrection. (shrink)

Hempel’s Dilemma remains at the center of the problem of defining physicalism. In brief, the dilemma asks whether physicalism should be defined by appeal to current or future physics. If defined by current physics, physicalism is almost certainly false. If defined by an ideal future physics, then physicalism has little determinable content. Montero and Papineau have innovatively suggested that the dilemma may be avoided by defining physicalism structurally. While their definition is one among many definitions, it is significant in that—if (...) successful—it would break the impasse for defining physicalism. I argue, however, that the structural definition fails because it counts metaphysical frameworks (crucially, versions of divine idealism) as “physicalist”—an unwelcome result for physicalists. This paper thus furthers the debate on the definition of physicalism and sheds light on the relationship between physicalism and idealism. (shrink)

Hempel’s Dilemma remains at the center of the problem of defining physicalism. In brief, the dilemma asks whether physicalism should be defined by appeal to current or future physics. If defined by current physics, physicalism is almost certainly false. If defined by an ideal future physics, then physicalism has little determinable content. Montero and Papineau have innovatively suggested that the dilemma may be avoided by defining physicalism structurally. While their definition is one among many definitions, it is significant in that—if (...) successful—it would break the impasse for defining physicalism. I argue, however, that the structural definition fails because it counts metaphysical frameworks as “physicalist”—an unwelcome result for physicalists. This paper thus furthers the debate on the definition of physicalism and sheds light on the relationship between physicalism and idealism. (shrink)

Several scholars have claimed that the decline of revealed or Scriptural mysteries in the early Enlightenment was a consequence of the trajectories of Reformed theology in the sixteenth and seventeenth centuries. Reformed theology's fideistic stance, it is claimed, undermined earlier frameworks for relating reason to revealed mysteries; consequently, rationalism emerged as an alternative to such fideism in figures like the Cambridge Platonists. This article argues that Reformed theologians of the seventeenth century were not fideists but re‐affirmed Medieval claims about the (...) eschatological concord of reason and revealed mysteries. Furthermore, the article suggests that early Enlightenment attitudes to religious mysteries owe more to innovations in Socinianism and Cambridge Platonism than to mainstream Reformed theology. (shrink)

The present study sought to determine the extent to which individuals'' ethical ideologies, as measured by Forsyth''s (1980) Ethics Position Questionnaire (EPQ), impacted the degree of punishment they advocated for differing ethical infractions, as well as their selection of non-ethics related variables that might be used to modify judgments of disciplinary action. The data revealed that individual ideology does impact both advocated punishment and choice of non-ethics related variables, but only in some measures. The data are discussed in terms of (...) potential moderating variables that could be examined in future studies. (shrink)

A commitment to receive input from stakeholders is often obligatory in the crafting of environmental policies. This requirement is presumed to satisfy certain conditions of democracy. In this article, by drawing from pragmatism, we examine the logic of participation and prerequisites of the meaningful game of asking for and giving reasons. We elaborate the nature and significance of three components—the game, the pleadings, and the reasons. We conclude by offering the conditions under which the stakeholder game might be considered legitimate.

Standard accounts of semantics for counterfactuals confront the true–true problem: when the antecedent and consequent of a counterfactual are both actually true, the counterfactual is automatically true. This problem presents a challenge to safety-based accounts of knowledge. In this paper, drawing on work by Angelika Kratzer, Alan Penczek, and Duncan Pritchard, we propose a revised understanding of semantics for counterfactuals utilizing machinery from generalized quantifier theory which enables safety theorists to meet the challenge of the true–true problem.

On April 16, 2007, Cho Seung-Hui used two semiautomatic handguns to kill 32 persons and then himself at Virginia Tech University in the largest campus shooting in U.S. history. Mr. Cho purchased his handguns from a pawnshop and a gun store in Virginia, where under state law a background check was conducted to determine whether he had any disqualifying criminal or mental health history. The paperwork for the background check was completed at the gun store, and the check itself was (...) conducted through an “instant” system facilitated by a toll-free telephone number. The entire transaction took approximately 20 minutes. At no point was Mr. Cho asked why he wished to purchase the guns. And although he had been deemed a potential danger to himself by a state magistrate in 2005 – which should have disqualified his purchase of a gun under federal law – this information never reached those conducting the background check. (shrink)

The United States and Canada regulate frearms, particularly handguns, quite differently. With only a few state and local exceptions, the U.S. approach emphasizes the ability of most individuals to purchase, possess, and carry handguns. By comparison, Canada has a form of restrictive licensing for handguns that places a premium on community safety. The authors first review the potential individual and community level harms and benefits associated with these differing fre-arm policies. Using this information, they explore the ethical dimensions of the (...) U.S. and Canadian approaches through three major themes of autonomy, prevention of harms, and social justice. The authors conclude that the Canadian approach is consistent with respect for the autonomy of persons, fosters the prevention of harms, and more appropriately furthers social justice. (shrink)

Standard accounts of semantics for counterfactuals confront the true–true problem: when the antecedent and consequent of a counterfactual are both actually true, the counterfactual is automatically true. This problem presents a challenge to safety‐based accounts of knowledge. In this paper, drawing on work by Angelika Kratzer, Alan Penczek, and Duncan Pritchard, we propose a revised understanding of semantics for counterfactuals utilizing machinery from generalized quantifier theory which enables safety theorists to meet the challenge of the true–true problem.

According to an influential contextualist solution to skepticism advanced by Keith DeRose, denials of skeptical hypotheses are, in most contexts, strong yet insensitive. The strength of such denials allows for knowledge of them, thus undermining skepticism, while the insensitivity of such denials explains our intuition that we do not know them. In this paper we argue that, under some well-motivated conditions, a negated skeptical hypothesis is strong only if it is sensitive. We also consider how a natural response on behalf (...) of DeRose appears to be equally available to his primary rival (viz., the sensitivity theorist). (shrink)

For at least the past three decades, injuries have been recognized as an important public health problem in the United States. In 2001, there were approximately 157,000 deaths due to injuries in the US. There were also almost 30 million non-fatal injury incidents.Injuries have been defined as: “…any unintentional or intentional damage to the body resulting from acute exposure to thermal, mechanical, electrical, or chemical energy or from the absence of such essentials as heat or oxygen”. Within public health, the (...) field of injury prevention and control is dedicated to reducing the burden of injuries on the lives of people around the world.Injury prevention seeks to reduce injuries by: 1) identifying risk factors, 2) designing interventions to address the risk factors, 3) implementing those interventions, 4) evaluating their effectiveness, and 5) replicating those that work. As with many other public health problems, interventions can target factors associated with the human or host, vehicle or vector, and the physical or social environment. (shrink)

For at least the past three decades, injuries have been recognized as an important public health problem in the United States. In 2001, there were approximately 157,000 deaths due to injuries in the US. There were also almost 30 million non-fatal injury incidents.Injuries have been defined as: “…any unintentional or intentional damage to the body resulting from acute exposure to thermal, mechanical, electrical, or chemical energy or from the absence of such essentials as heat or oxygen”. Within public health, the (...) field of injury prevention and control is dedicated to reducing the burden of injuries on the lives of people around the world.Injury prevention seeks to reduce injuries by: 1) identifying risk factors, 2) designing interventions to address the risk factors, 3) implementing those interventions, 4) evaluating their effectiveness, and 5) replicating those that work. As with many other public health problems, interventions can target factors associated with the human or host, vehicle or vector, and the physical or social environment. (shrink)

Firearms were associated with 30, 136 deaths in the United States in 2003. Most guns are initially sold to the public through a network of retail dealers. Licensed firearm dealers are an important source of guns for criminals and gun traffickers. Just one percent of licensed dealers were responsible for more than half of all guns traced to crime. Federal law makes it difficult for ATF to inspect and revoke the licenses of problem gun dealers. State licensing systems, however, are (...) a greatly under-explored opportunity for firearm dealer oversight. We identify and categorize these state systems to identify opportunities for interventions to prevent problem dealers from supplying guns to criminals, juveniles, or gun traffickers. Just seventeen states license gun dealers. Twenty-three states permit routine inspections of dealers but only two mandate that those inspections occur on a regular basis. Twenty-six states impose record-keeping requirements for gun sales. Only thirteen states require some form of store security measures to minimize firearm theft. We conclude with recommendations for a comprehensive system of state licensing and oversight of gun dealers. Our findings can be useful for the coalition of more than fifty U.S. mayors that recently announced it would work together to combat illegal gun trafficking. (shrink)

Firearms were associated with 30,136 deaths in the United States in 2003; of these, 11,920 were homicides. For every firearm homicide, there are four people who suffer non-fatal firearm assaults. Like many other consumer products in the US, most guns are initially sold to the public through a network of retail dealers. Persons in the business of selling firearms must obtain a federal firearm dealer's license. There were more than 54,000 federally licensed gun dealers in the United States in 2005, (...) though this reflects a seventy-eight percent decline since 1994. Some states also require a state license to sell firearms.Licensed firearm dealers are an important source of guns for criminals and gun traffickers. In one analysis of gun trafficking investigations conducted by the Bureau of Alcohol, Tobacco and Firearms, licensed dealers accounted for a plurality of all guns diverted to the illegal market. (shrink)

Firearm violence is a major public health problem in the United States. In 2000, firearms were used in 10,801 homicides – two-thirds of all homicides in the U.S. – and 533,470 non-fatal criminal victimizations including rapes, robberies, and assaults. The social costs of gun violence in the United States are also staggering, and have been estimated to be on the order of $100 billion per year.Illegal gun carrying, usually concealed, in public places is an important risk factor for firearm-related crime. (...) In the 1980s and 1990s, police departments across the country began to develop and implement strategies to address illegal weapons carrying. Often these strategies have involved aggressive efforts to identify and physically search individuals suspected of illegally carrying a firearm. (shrink)

Firearm violence is a major public health problem in the United States. In 2000, firearms were used in 10,801 homicides – two-thirds of all homicides in the U.S. – and 533,470 non-fatal criminal victimizations including rapes, robberies, and assaults. The social costs of gun violence in the United States are also staggering, and have been estimated to be on the order of $100 billion per year.Illegal gun carrying, usually concealed, in public places is an important risk factor for firearm-related crime. (...) In the 1980s and 1990s, police departments across the country began to develop and implement strategies to address illegal weapons carrying. Often these strategies have involved aggressive efforts to identify and physically search individuals suspected of illegally carrying a firearm. (shrink)

Participants struck 500 golf balls to a concealed target. Outcome feedback was presented at the subjective or objective threshold of awareness of each participant or at a supraliminal threshold. Participants who received fully perceptible feedback learned to strike the ball onto the target, as did participants who received feedback that was only marginally perceptible . Participants who received feedback that was not perceptible showed no learning. Upon transfer to a condition in which the target was unconcealed, performance increased in both (...) the subjective and the objective threshold condition, but decreased in the supraliminal condition. In all three conditions, participants reported minimal declarative knowledge of their movements, suggesting that deliberate hypothesis testing about how best to move in order to perform the motor task successfully was disrupted by the impoverished disposition of the visual outcome feedback. It was concluded that sub-optimally perceptible visual feedback evokes implicit processes. (shrink)

Abstract:By combining normative philosophy and empirical social science, we craft a research framework for assessing differential expectations embodied in normative conceptions of the economic social contract in the United States. We argue that there are distinct views of such a contract grounded in individualist and communitarian philosophical ideologies. We apply this framework to organizational downsizing, postulating that certain human resource practices, in combination with the respective ideological orientations, will affect perceptions of the justice of downsizing policies.

Although social contracts theory has been applied to organizations (Donaldson & Dunfee, 1994), rarely has the theory been tested empirically. This article uses the traditions of communitarianism and individualism to instantiate an ideal-type economic social contract. We asked 269 subjects to complete the Ideological Orientation Scale and to make judgments on eight downsizing scenarios. Using social judgment theory, we assess the direct and indirect influences of ideology on judgments of fairness. Our findings suggest that ideology indeed shapes individual’s conceptions of (...) organizational fairness. (shrink)

Duncan Pritchard has argued that his basis-relative anti-luck construal of a safety condition on knowing avoids the problem with necessary truths that safety conditions are often thought to have, viz., that beliefs the contents of which are necessarily true are trivially safe. He has further argued that adding an ability condition to truth, belief, and his anti-luck safety conditions yields an adequate account of knowledge. In this paper, we argue that not only does Pritchard’s anti-luck safety condition have a problem (...) with necessary truths, adding an ability condition is of no help. Indeed, the same sort of case that precipitates Pritchard’s introduction of an ability condition shows the inadequacy of his completed anti-luck account of knowledge. Moreover, reconstruing safety as an anti-risk condition as Pritchard has recently done does not fix the problem we’ve identified. We conclude by entertaining a radical suggestion to the effect that the failures of safety-based accounts of modal knowledge are due to failures of doxastic success rather than failures to satisfy an anti-luck (or anti-risk) condition. Accepting this radical suggestion makes available the view that there is, after all, no special problem between safety and necessary truths. (shrink)

The Monographs produced by the International Agency for Research on Cancer (IARC) apply rigorous procedures for the scientific review and evaluation of carcinogenic hazards by independent experts. The Preamble to the IARC Monographs, which outlines these procedures, was updated in 2019, following recommendations of a 2018 expert Advisory Group. This article presents the key features of the updated Preamble, a major milestone that will enable IARC to take advantage of recent scientific and procedural advances made during the 12 years since (...) the last Preamble amendments. The updated Preamble formalizes important developments already being pioneered in the Monographs Programme. These developments were taken forward in a clarified and strengthened process for identifying, reviewing, evaluating and integrating evidence to identify causes of human cancer. The advancements adopted include strengthening of systematic review methodologies; greater emphasis on mechanistic evidence, based on key characteristics of carcinogens; greater consideration of quality and informativeness in the critical evaluation of epidemiological studies, including their exposure assessment methods; improved harmonization of evaluation criteria for the different evidence streams; and a single-step process of integrating evidence on cancer in humans, cancer in experimental animals and mechanisms for reaching overall evaluations. In all, the updated Preamble underpins a stronger and more transparent method for the identification of carcinogenic hazards, the essential first step in cancer prevention. (shrink)

Rare copy number variants have a prominent role in the aetiology of schizophrenia and other neuropsychiatric disorders. Substantial risk for schizophrenia is conferred by large CNVs at several loci, including microdeletions at 1q21.1, 3q29, 15q13.3 and 22q11.2 and microduplication at 16p11.2. However, these CNVs collectively account for a small fraction of cases, and the relevant genes and neurobiological mechanisms are not well understood. Here we performed a large two-stage genome-wide scan of rare CNVs and report the significant association of copy (...) number gains at chromosome 7q36.3 with schizophrenia. Microduplications with variable breakpoints occurred within a 362-kilobase region and were detected in 29 of 8,290 patients versus 2 of 7,431 controls in the combined sample. All duplications overlapped or were located within 89 kilobases upstream of the vasoactive intestinal peptide receptor gene VIPR2. VIPR2 transcription and cyclic-AMP signalling were significantly increased in cultured lymphocytes from patients with microduplications of 7q36.3. These findings implicate altered vasoactive intestinal peptide signalling in the pathogenesis of schizophrenia and indicate the VPAC2 receptor as a potential target for the development of new antipsychotic drugs. © 2011 Macmillan Publishers Limited. All rights reserved. (shrink)

Graphical AbstractScience and technology consortia provide a viable solution for the recent unsustainable academic growth in biomedical research.